DNA-R1B1C7-L Archives

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Subject: [DNA-R1B1C7] R1b1c7 and DYS 458 = 18
Date: Sat, 19 Jan 2008 21:05:42 EST

I'm just running through markers we're seeing in Donegal clans which are off
the R1b1c7 modal.

Another example is DYS 458. Both Mclaughlins and Dohertys are modal at DYS
458 = 18. But not all of either surname have this value. Many are 17. I
don't have the exact figures for the Dohertys but are McLaughlin results are:

McLaughin samples

15 of 21 have DYS 458 = 18
1 has DYS 458 = 19
5 have DYS 458 = 17

I checked Ysearch for the prevalence of this mutation at DYS 458 (modal
R1b1c7 = 17).

As before, I used the first 12 markers of the R1b1c7 modal, added DYS 458 =
18, 1 GD, 13 markers.

Ysearch returned 482 matches, not all of which had DYS 458 = 18 thanks to
the 1 GD parameter. In total, there were 166 samples with DYS 458 = 18. That
works out to 34.4% of the R1b1c7 matches pulled up in the search. Many of
the entries were McLaughlins and Dohertys and other samples that previously
came up in a similar search for DYS 447 = 24. That was hardly a surprise.
Since the results were heavily overweighted with McLaughlins and Dohertys, I
reduced the sampling of each to four. That reduced the matching figure to 145
which is still 30% of the results.

It's difficult to categorize the results by surnames and the list is huge so
I won't post it here. But those R1b1c7 with DYS 458 = 18 seem to cover a
much broader geographical range than those with DYS 447 = 24. There are lots
of Scottish surnames in the list, including Millikans, Dunbars, Grierson,
McAdams and a lot of Burgesses.

David Wilson's breakdown of DYS 458 = 18 seems much lower than what I found
(19% vs. 30%).

I don't know what to make of the fact that DYS 458 = 18 is modal in
Mclaughlins and Dohertys but not present in every sample. It's present in other
Donegal DNA samples but not overwhelmingly.


John





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