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Archiver > DNA-R1B1C7 > 2007-08 > 1187041460


From:
Subject: Re: [DNA-R1B1C7] Network.exe
Date: Mon, 13 Aug 2007 17:44:20 EDT


David - here are a couple of other samples you might throw in the mix if
you're still working on genetic distance.

Duncan BK7DE Duncan HJSHQ Duncan DMD4J Ashley HDGND Ashley PJ72T

These came from John McEwen's R1b clustering chart. There are actually a
few more samples of each available on Ysearch but they are just more exact
matches (probably cousins) so I eliminated a few of them.

The Duncan surname is thought to be Scottish; Ashley is from England.

I set up a few histograms for Mclaughin, Ewing, Duncan and Ashley samples.
Then used Anne Turner's Mutation Calculator on the results. While the
dates will obviously vary depending on the assumed mutation rate - one thing
remains constant - the difference in the number of mutations. And these I assume
can be further weighted by fast vs. slow moving markers, although I haven't
attempted to do that and Anne's calculator doesn't take that into account.

It looks to me like at least based on the number of raw mutations at 37
markers the Duncans, Ashleys and Ewings consistently have more mutations than
the McLaughlins.


Mutations vs. the R1b1c7 modal

Duncan/Ashley (5 samples)

*GD = 0 0 ea (0.0%)
*GD = 1 0 ea (0.0%)
*GD = 2 0 ea (0.0%)
*GD = 3 0 ea (0.0%)
*GD = 4 0 ea (0.0%)
*GD = 5 0 ea (0.0%)
*GD = 6 0 ea (0.0%)
*GD = 7 0 ea (0.0%)
*GD = 8 5 ea (100.0%)
*GD = 9 0 ea (0.0%)
*GD =10 0 ea (0.0%)
*GD =11 0 ea (0.0%)
*GD =12 0 ea (0.0%)
*GD =13 0 ea (0.0%)
*GD =14 0 ea (0.0%)
*GD =15 0 ea (0.0%)

Range 8-8

Ewing (14 samples)

*GD = 0 0 ea (0.0%)
*GD = 1 0 ea (0.0%)
*GD = 2 0 ea (0.0%)
*GD = 3 0 ea (0.0%)
*GD = 4 0 ea (0.0%)
*GD = 5 0 ea (0.0%)
*GD = 6 3 ea (21.4%)
*GD = 7 6 ea (42.8%)
*GD = 8 2 ea (14.3%)
*GD = 9 2 ea (14.3%)
*GD =10 1 ea (07.0%)
*GD =11 0 ea (0.0%)
*GD =12 0 ea (0.0%)
*GD =13 0 ea (0.0%)
*GD =14 0 ea (0.0%)
*GD =15 0 ea (0.0%)

Range 6-8

McLaughlin (14 samples)

*GD = 0 0 ea (0.0%)
*GD = 1 0 ea (0.0%)
*GD = 2 0 ea (0.0%)
*GD = 3 1 ea (21.4%)
*GD = 4 0 ea (0.0%)
*GD = 5 7 ea (50.0%)
*GD = 6 3 ea (21.5%)
*GD = 7 2 ea (14.30%)
*GD = 8 1 ea (21.4%)
*GD = 9 0 ea (0.0%)
*GD =10 0 ea (0.0%)
*GD =11 0 ea (0.0%)
*GD =12 0 ea (0.0%)
*GD =13 0 ea (0.0%)
*GD =14 0 ea (0.0%)
*GD =15 0 ea (0.0%)

Range of 5-7


Anne Turner's Mutation Calculator
.0024 mutation rate
30 years = generation


Duncan/Ashley
Range = 8-8

37 markers
.0024 mutation rate
90 events TMRCA 2700 years (693 BC)


Ewing
Range = 6-9

37 markers
.0024 mutation rate
68 events (6) 2040 TMRCA (33 BC)
90 events (8) 2700 TMRCA (693 BC)
Range of 33 BC to 693 BC.

McLaughlin
Range 5-7

37 markers
.0024 mutation rate
56 events (5) 1680 TMRCA (327 A.D.)
79 events (7) 2370 TMRCA (363 BC)
Range of 327 AD. to 363 BC.


I tried the same data set in Network using 1 mutation every 980 years but
the results were so far off the figures of Anne's calculator I don't trust
them at all (7500 years TMRCA).


John















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