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Archiver > DNA-R1B1C7 > 2007-08 > 1186878996


From:
Subject: Re: [DNA-R1B1C7] Network.exe
Date: Sat, 11 Aug 2007 20:36:36 EDT



In a message dated 8/11/2007 11:36:31 A.M. Central Standard Time,
writes:

Bottom line, I think if we are comparing full 37-marker panels, we should
not be using average per locus rates as low as 0.002 and certainly not
0.00069. And we should probably not be using 25 year generation times, at
least not in the last 400 years among Scottish Presbyterians. I am by no
means expert, but I think if we want to do calculations about the MRCA of
the R1b1c7 McLaughlins and Ewings, we should use fewer markers and
Chandler's rates.

Try this:
393, 19, 426, 388, 389-1, 392, 459a, 459b, 455, 454, 437, 448, YCA-IIa/b,
and 438 with an average mutation rate of 0.00088 per locus, or 0.0132 for
the 15-marker panel. I think I'll go to work on this now, but I'm not sure
I'll have time to finish before other responsibilities shoulder this project
aside.



David, that would be an interesting approach. It would take a little work
but you could set up that data set in the McGee utility for Fluxus charts. I
also agree about the 25 year generation times. There was a huge discussion
on this a while back on the GEN-DNA list and most people used 30 or higher as
an average.

I'm not getting what appear to be accurate readings for either the
Dohertys or McLaughlins using the figures borrowed from the Trinity study.

John



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